Carmen Marsit's research, teaching, and service is focused broadly on understanding the molecular mechanisms responsible for mediating the impact of the environment in human disease, utilizing to inter- and multi-disciplinary research methods. His research program has focused on two distinct, yet highly related biologic processes: environmental carcinogenesis and human development. In those settings, he studies a variety of molecular alterations, with a growing interest on –omics technologies, which may be responsible, in a significant part, for cancer, adverse pregnancy outcomes, and common and rare conditions of childhood including obesity, growth, and behavioral disorders. He has significant expertise in environmental epigenomics, incorporating studies of the impact of the environment, including chemical, physical, and psychosocial factors, on the mechanisms controlling the fundamental cellular process of gene expression control, and how alterations or variation to these features impact health and disease. This research program fits at the interface of basic and population sciences, providing a sound scientific basis to studying a mechanism underlying the environmental contribution to health outcomes. The overarching goal of this work is to both provide important biologic and mechanistic evidence to support policies related to the control of environmental contaminants, and to provide insights into novel prevention and intervention strategies.
Dr. Marsit received his Ph.D. in the Biological Sciences in Public Health at Harvard University, which was followed by a postdoctoral fellowship at the Harvard School of Public Health. Through these experiences he has obtained extensive training and expertise in molecular biology, genetics, epidemiology, biostatistics, environmental health and cancer molecular epidemiology. Prior to joining the faculty in Environmental Health at Emory in 2016, he held faculty appointments in Pathology and Laboratory Medicine at Brown University (2007-2011), and in Pharmacology and Toxicology and Epidemiology at the Geisel School of Medicine at Dartmouth (2011-2016). His research program has been supported by a number of NIH R01 grants, and he participates in NIEHS/EPA Children's Environmental Health Center Research Program Projects at Dartmouth and Emory, as well as in a number of large, multi-center cohorts and consortium focused on Children's Environmental Health. He is now Director of the NIEHS Environmental Health Core Center at Emory, the HERCULES Exposome Research Center (P30). Dr. Marsit also has a strong committment to the training of the next-generation of population researchers and now serves as Director of the NIEHS-funded T32 Training Program in the Environmental Health Sciences and Toxicology.
For a full list of up to date publications, visit Dr. Marsit's Google Scholars page.
Areas of Interest
- Adolescent Health/Child Health
- Biomedical Sciences
- Cancer Prevention
- Environmental Health
- Maternal and Child Health
- Bachelors of Science 2000, Lafayette College
- Ph.D. 2004, Harvard University
- EHS 799R: Dissertation Research
Affiliations & Activities
Member: Infectious, Reproductive, Asthma and Pulmonary Conditions (IRAP) Study Section, 2016-2020
Member: Maternal Exposures Working Group, Pediatric HIV/AIDS Cohort Studies, 2011-present; NIH ECHO Steering Committee, 2016-present
Advisory Committee Chair: Environmental Health Disparities Research Center, University of Southern California, 2016-present
Advisory Committee Member: Columbia University NIEHS Center for Environmental Health in Northern Manhattan, 2016-present; University of Kentucky Superfund Research Program, 2018-present.
Member: International Society for Environmental Epidemiology, American Association for Cancer Research, International Society for Children’s Health and the Environment, US DOHaD Society
- Everson TM, Armstrong DA, Guerin DJ, Punshon T, Jackson BP, Lambertini L, Chen J, Karagas MR, Marsit CJ, 2018, Cadmium-associated differential methylation throughout the placental genome: epigenome-wide association study of two US birth cohorts., Environmental Health Perspectives, 126,
- Deyssenroth MA, Gennings C, Liu SH, Peng S, Hao K, Lambertini L, Jackson BP, Karagas MR, Marsit CJ, Chen J., 2018, Intrauterine multi-metal exposure is associated with reduced fetal growth through modulation of the placental gene network, Environment International, ,
- Deyssenroth MA, Peng S, Hao K, Lambertini L, Marsit CJ, Chen J, 2017, Whole-transcriptome analysis delineates the human placenta gene network and its associations with fetal growth, BMC Genomics, 18, 520
- Green BB, Karagas MR, Punshon T, Jackson B, Robbins DJ, Houseman EA, Marsit CJ., 2016, Epigenome-Wide Assessment of DNA Methylation in the Placenta and Arsenic Exposure in the New Hampshire Birth Cohort Study (USA), Environmental Health Perspectives, 124, 1253-60
- Kingsley SL, Eliot MN, Whitsel EA, Huang YT, Kelsey KT, Marsit CJ, Wellenius GA, 2016, Maternal residential proximity to major roadways, birth weight, and placental DNA methylation, Environment International, 92-93, 43-9
- Stroud LR, Papandonatos GD, Parade SH, Salisbury AL, Phipps MG, Lester BM, Padbury JF, Marsit CJ. , 2016, Prenatal Major Depressive Disorder, Placenta Gluocorticoid and Serotonergic Signaling, and Infant Cortisol Response, Psychosomatic Medicine, 78, 979-90
- Appleton AA, Murphy MA, Koestler DC, Lesseur C, Paquette AG, Padbury JF, Lester BM, Marsit CJ, 2016, Prenatal Programming of Infant Neurobehavior in a Healthy Population, Paediatr Perinat Epidemiol, 30, 367-75
- Paquette AS, Green BB, Armstrong DA, Houseman EA, Lester BM, Marsit CJ, 2016, Regions of variable DNA methylation in human placenta associated with newborn neurobehavior, Epigenetics, 11, 603-13
- Green BB, Kappil M, Lambertini L, Armstrong DA, Guerin DG, Lester BM, Chen J, Marsit CJ., 2015, Expression of imprinted genes in placenta is associated with infant neurobehavioral development, Epigenetics, 10, 834-41
- Kappil M, Green BB, Armstrong DA, Lambertini L, Marsit CJ, Chen J, 2015, Placental Expression Profile of Imprinted Genes Impacts Birth Weight, Epigenetics, 10, 842-9
- Marsit CJ, Koestler D, Christensen BC, Karagas MR, Houseman EA, & Kelsey KT. , 2011, DNA methylation array analysis identifies profiles of blood-derived DNA methylation associated with bladder cancer. , Journal of Clinical Oncology, 29, 1133-9