Rollins School of Public Health | Faculty Profile
Emory Rollins School of Public Health

Mary  Kelley

Research Professor

Faculty, Biostatistics and Bioinformatics

Dr. Kelley has worked with the Emory Psychiatry department studying the biological predictors (imaging, genetics, immune) of treatment response in depression. She is well-versed in the challenges of research involving complex behavioral assessments and evaluation of interventions in behaviorally disordered patients, and has an extensive background in statistical analysis relevant to studies of human behavior including clinical trials of psychopharmacological therapies, scale/survey development and evaluation, and imaging applications in psychiatric research. In addition to the studies in depression treatment, she is currently involved in a study of the effects of substance use and early life events in first episode schizophrenia patients, and an interesting new treatment for very severely ill depressed patients that involves deep brain stimulation (DBS).  Dr. Kelley also has extensive experience in health services research having worked for at the Center for Health Equity and Research Promotion (CHERP - VA Pittsburgh) for 6 years. At that time, she was involved in a number of studies on subjects with CHD including assessment of treatment practices, the effects of alcohol use, and predictive risk models for cardiovascular outcomes. It was in this arena she honed her skills in multilevel (hierarchical) modeling, which she continues to use in collaboration with BSHE projects within RSPH.  Her methodology work evolves from her extensive experience with categorical (primarily ordinal) data, and is focused on the issues of non-response evident in many behavioral scales that result in “zero inflation”, use of ordinal data in the development of latent constructs, and assessment of longitudinal response. 

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Contact Information

Rollins School of Public Health , 1518 Clifton Road NE

Atlanta , GA 30322

Phone: (404) 712-0804

Fax: (404) 727-1370


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Areas of Interest

  • Imaging
  • Mental Health
  • Statistical Modeling


  • , , Association of pre-onset cannabis, alcohol, and tobacco use with age at onset of prodrome and age at onset of psychosis in first-episode patients, Am J Psychiatry, 166, 1251-1257
  • , , Zero inflation in ordinal data: Incorporating susceptibility of response through the use of a mixture model., Statistics in Medicine, 27, 3674-3688
  • , , Longitudinal progression of negative symptoms in schizphrenia: A new look at an old problem., Schizophr Res, 105, 188-196
  • , , Subcallosal cingulate deep brain stimulation for treatment-resistant unipolar and bipolar depression, Arch Gen Psychiatry, 69(2), 150-8
  • , , Toward a neuroimaging treatment selection biomarker for major depressive disorder., JAMA Psychiatry, ,
  • , , Subscale structure for the Positive and Negative Syndrome Scale (PANSS): A proposed solution focused on clinical validity. , Psychiatry Research, 205, 137-142