Collaborations, Cores, and Research Centers

Scientific collaboration is a crucial element to public health and a vital aspect of Rollins’ Department of Biostatistics and Bioinformatics. Our department is home to various research cores and groups offering comprehensive statistical services to Rollins faculty, staff, and students, other divisions of the Woodruff Health Sciences Center, and throughout Emory University.

Research Cores

The Biostatistics Collaboration Center (BCC) provides biostatistical consultation services to students, faculty, and staff at Rollins, the Woodruff Health Sciences Center, and across Emory University.

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The Biostatistics, Epidemiology & Research Design (BERD) program supplies comprehensive biostatistical and epidemiological support to investigators through the Atlanta Clinical & Translational Science Institute.

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The Center for Biomedical Imaging Statistics (CBIS) conducts research on statistical methods for analyzing data from biomedical imaging studies, such as brain, cardiac, breast, and prostate imaging. Learn more>>

The Emory University Department of Medicine has a Data Analytics and Biostatistics (DAB) Core that seeks to provide high-quality biostatistics and IT Data management services by leveraging existing services at Rollins and the Information Technology Department. 

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Emory University’s Center for AIDS Research (CFAR) has a Biostatistics and Biomedical Informatics Core that works to assist AIDS researchers with data management, statistical analysis, data monitoring, and more.

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Emory’s Winship Cancer Institute includes a Biostatistics and Bioinformatics Shared Resource assisting cancer researchers in study design, data collection, data analysis, and interpretation of results.

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In addition to these broad cores, the department also conducts methodological research and is also home to data coordinating centers for clinical trials, data management centers for large global health investigations, and research groups in cardiology, diabetes, and environmental health.

Other Collaborative Projects

Studies in major depressive disorder (MDD): Dr. Mary Kelley is involved in multiple trials of treatment response in MDD using biomarkers, including genetics and imaging, as well as traditional demographic and behavioral predictors, to develop algorithms for treatment choice in first-episode and previously diagnosed patients with MDD. She is also involved in a pioneering study of deep brain stimulation for patients with treatment-resistant depression.

Faculty: Mary Kelley

Infant aphakia treatment study (IATS): IATS is a randomized, multicenter clinical trial funded by the National Eye Institute to study infants born with a cataract in one eye. All the infants will have the lens with the cataract removed and will then be randomized either to wear a contact lens or to have an intraocular lens (IOL) implanted. The advantage of the contact lens compared to the IOL is that the power of the contact lens can be changed as the eye grows. However, the contact lens must be removed, cleaned, and re-inserted in the child's eye on a regular basis, which is a challenge for many parents. If the parents stop using the contact lens, the child is likely to lose sight in the eye. The main outcomes of the study include visual acuity, the occurrence of complications, and quality of life measures. The data coordinating center for the study is housed in the Department of Biostatistics and Bioinformatics, and is a collaboration with the Department of Epidemiology.

Faculty: Qi Long

Emory hosts one of four NIAID-funded tuberculosis research units (TBRUs). Our TBRU project, Role of Antigen-Specific T Cell Responses in the Control of TB, is led by investigators at Emory University and NYU School of Medicine. Human studies will be conducted in both Atlanta, Georgia, and Kenya in collaboration with investigators at the DeKalb County (Georgia) Board of Health, the Kenya Medical Research Institute, and CDC-Kenya.

Studies of TB in nonhuman primates will be done by experts at Yerkes National Primate Research Center and the Tulane National Primate Research Center. Other collaborating institutions include the La Jolla Institute of Allergy and Immunology, Aeras, and the U.S. Centers for Disease Control and Prevention. The assembled team possesses a wide range of knowledge and expertise, and is poised to generate improved understanding of TB immunity to contribute to the elimination of TB.  Faculty and research staff in the Department of Biostatistics and Bioinformatics, including Lance Waller, Hao Wu, Azhar Nizam, Andrea Knezevic, Lisa Elon, and Shirin Jabbarzadeh lead the Data Management Center for TBRU-ASTra including clinical data management, specimen tracking, and analysis of data marking the transition from latent to active TB infection.

http://tbru.emory.edu/index.html

Faculty: Lance Waller, Hao Wu, Azhar Nizam, Lisa Elon

A number of faculty and students work closely with the Division of Cardiology and the School of Medicine, particularly the Emory Clinical Cardiovascular Research Institute, the Division of Cardiothoracic Surgery, and the Emory Heart and Vascular Center. Collaborative projects with Cardiology involve pathophysiology and treatment of cardiovascular diseases, vascular function, atherosclerosis, heart failure, medical imaging, cost effectiveness, and cardiovascular population research and risk assessment. Collaborative projects with Cardiothoracic Surgery include the development and evaluation of innovative surgical methods of performing complex coronary revascularization, repairing thoracic aortic aneurysms, cost-effectiveness of cardiovascular disease diagnostic testing, and repairing and/or replacing damaged heart valves.

Many areas of methodological research have application to problems in cardiovascular disease management, including survival analysis, longitudinal data analysis, multivariate and latent variable models, missing data problems, randomization trials, causal inference, and spatial analysis.

Faculty: Jose Binongo, Yi-An Ko, Qi Long, Christina Mehta

Biostatistics and Bioinformatics faculty also work closely with faculty across the university who are conducting HIV research. Many of these connections are facilitated by the Emory Center for AIDS Research, for which the department houses a Biostatistics and Biomedical Informatics Core. Collaborators come from the School of Medicine, Rollins School of Public Health, Yerkes National Primate Research Center, and the School of Nursing.

Areas of research within the field of HIV include low-level viremia, pharmacokinetic/pharmacodynamics studies of new drugs or existing drugs in different HIV reservoirs, aging, cardiovascular disease, pregnancy trends, depression, female genital tract biome, PTSD, physical activity, continuum of care, and cellular expression. Emory University is also a site for the Women’s Interagency HIV Study, a large multi-site longitudinal study on the health of HIV positive and high-risk HIV negative minority women.

Many areas of methodological research have application to problems in HIV, including survival analysis, longitudinal data analysis, multivariate and latent variable models, missing data problems, randomization trials, and causal inference. 

Faculty: Kirk Easley, Eugene Huang, Yijuan Hu, Bob Lyles, Christina Mehta, Hao Wu, Tianwei Yu