Epidemiology Courses

Current students: Course syllabi from previous semesters are available on S:\Syllabi. Please direct any questions to Jena Black or Nicole Regan.

Course # Title Description
EPI 504 (2)

Fundamentals of Epidemiology (Spring)


Emphasizes the underlying concepts of the epidemiological approach, stressing study design. Discusses the calculation and interpretation of measures of frequency, association, and public health impact. Discusses sources of study error including the influence of chance, bias, confounding, and effect modification. Basic concepts of standardizing rates, surveillance, and screening are also introduced. Non-EPI students only who have not taken EPI 530.
EPI 510 (1)

Introduction to Genetic and Molecular Epidemiology (Fall)


This course will introduce basic principles of genetic and molecular epidemiology thought interactive discussion with leading researchers in the field. This is a stand-alone course but is also a prerequisite for the Genetic and Molecular Epidemiology Certificate Program.
EPI 515 (3)

Transforming Public Health Surveillance (Spring)


Teaches the basic principles of public health surveillance, including the establishment of a public health surveillance program, the collation and analysis of data, and the preparation and distribution of a report. Helps students to recognize the importance of a direct association between a public health surveillance program and public health action. Helps students become familiar with the use of computers in public health surveillance, with public health surveillance systems conducted in developed, as well as developing countries, and with public health surveillance programs as applied to all public health problems involving either infectious or noninfectious diseases.
Prerequisite: EPI 504 or EPI 530. Cross-listed with GH 515.
EPI 516 (2)

Issues in Women's Health (Fall, even years)

Vaccarino, Hartman

This course presents issues in women of being female but not pathologies of reproduction. These include cardiovascular disease, osteoporosis, and breast and cervical cancer. In addition, health problems related to the physiological and psychological aspects of being female are addressed. These include depression, premenstrual syndrome, addictive behavior, and violence perpetrated by and against women. Prerequisite: EPI 504 or EPI 530 and BIOS 500.
EPI 518 (2)

Practical Introduction to Survey Design (Winter. may not be offered every year)

Sullivan, Siegler

This short course is a practical introduction to survey research, seeking to provide students with hands-on skills to develop and implement electronic surveys. In the course, students will work in teams to develop and launch a survey, with the following phases: item development, item cognitive assessment, electronic survey programming, survey recruitment on Facebook (each team will have a recruitment budget), collection of survey data from online participants, and presentation of survey results. The course focus is predominantly on electronic survey provision, including web-based implementations. Other areas of emphasis include item creation, item optimization through qualitative techniques, sources of survey error, and strategies to mitigate survey error.
EPI 523 (1)

Correctional Healthcare (Spring)


Ten million persons pass through a jail or prison each year in the United States. This half-semester, seminar-style course will explore the possible impact of the criminal justice system on the epidemiology of infectious diseases and on health indicators in general. The correctional setting will be used as a case study to illustrate how environment, public policy, behavior and biology all interact to determine the well-being of a population. Lessons learned from studying correctional health are applicable to understanding the determinants of health for other institutionalized populations and in other controlled settings. We have plans to make a field trip to a local correctional facility.
EPI 530 (4)

Epidemiologic Methods I (Fall)

Various Instructors

Emphasizes the concepts and premises of the science of epidemiology. Methods of hypothesis formulation and evaluation are stressed. Techniques for quantifying the amount of disease (or other health indicator) in populations are introduced, followed by discussion of epidemiologic study designs useful for identifying etiologic factors and other relevant correlates of disease. Students gain facility with the calculation of basic epidemiologic measures of frequency, association, and impact. The concepts of random variability, bias, and effect modification are examined in detail. The use of stratified analysis, including Mantel-Haenszel techniques, is explored. Inferences from study results are discussed. Students are required to analyze and critique studies from the current medical and scientific literature. Prerequisite/concurrent: BIOS 500.
EPI 533 (1)

Programming in SAS (Fall, Spring)

Various Instructors

This is an applied computer analytic course utilizing a database to cover univariate analysis, logistic regression. Permission only in Fall. Required for epidemiology majors.
EPI 534 (3)

Epidemiologic Methods II (Spring)


Emphasizes the statistical foundations of epidemiological methods. The concepts of matching, confounding, effect modification and interaction are further developed. Modeling techniques for epidemiological data analysis are presented, including logistic regression for matched and unmatched studies. Some survival analysis methods will be examined. Statistical packages such as SAS are used. Required for epidemiology majors.
Prerequisites: EPI 530, BIOS 500, and BIOS 501/591P (BIOS 501 may be taken concurrently).
EPI 535 (2)

Field Epidemiology (Spring)


Uses a series of case studies to teach the principles and practice of epidemiology, ranging from surveillance and descriptive epidemiology to outbreak investigations and analytic methods. Focuses on the use of sound epidemiologic judgment. Cross listed with GH 535.
Prerequisite: EPI 530.
EPI 536 (2)

Applied Data Analysis (Fall)


Prerequisites: EPI 530, BIOS 500, and EPI 534 or BIOS 501. The purpose of this course is to prepare the student for analysis of epidemiologic data from various study designs including cross-sectional, case-control, and follow-up studies. The student will have the opportunity to apply the methods taught in the epidemiology methods sequence to actual data sets. After completion of the course, the student will be prepared to do the data analysis for their thesis. The course will use the statistical program, Stata, for all analyses and therefore some time will be spent in learning the fundamentals of Stata. We will analyze multiple data sets and apply epidemiologic and statistical methods such as exact tests for 2x2 tables, stratified analysis, logistic regression, and survival techniques appropriate for epidemiologists. The course will be applied and will emphasize the use of Stata to solve various epidemiologic problems using a wide range of data sets.
EPI 537 (2)

Epidemiology of Chronic Disease (Fall)

Alonso, Vaccarino

Emphasis is placed on the distribution and determinants of chronic disease within the population. Research design and analysis are not the primary focus of the course, but methodological issues are considered when pertinent to the interpretation of findings. Prerequisites: EPI 530 (concurrent okay).
EPI 538 (2)

Advanced Epidemiological Methods I (Spring)


Covers a wide variety of topics in epidemiological methodology. Topics will include basic epidemiological measures, confounding, misclassification, selection bias, types of case-control studies, Berkson estimation of epidemiological parameters. Prerequisites: EPI 530, EPI 534, BIOS 500, BIOS 501 (EPI 534 and BIOS 501 may be taken concurrently). Cross-listed with EPI 738.
EPI 540 (2)

Case Studies in Infectious Disease Epidemiology (Fall)


Provides training in the investigation, control, and prevention of infectious diseases by both descriptive and analytic epidemiological techniques. Students work with infectious diseases of national and international interest. Prerequisites/concurrent: EPI 504 or EPI 530 and BIOS 500 or permission of instructor. Cross-listed with GH 517.
EPI 541 (2)

Hospital/Healthcare Epidemiology (Spring)


This course will provide training in the investigation, control, and prevention of hospital acquired infectious diseases and other hospital events by the use of appropriate epidemiologic techniques, both descriptive and analytic. Prerequisites/concurrent: EPI 504 or EPI 530 and BIOS 500.
EPI 542 (1)

Tuberculosis: A Re-emerging Health Problem (Spring)

Gandhi, Vernon

To provide training in the domestic and international public health aspects of tuberculosis; its epidemiology and diagnosis, the theory and practice of treatment, and means of prevention in developed and developing countries; and the interaction between HIV and tuberculosis. Prerequisite: EPI 504, or EPI 530. Cross-listed with GH 562.
EPI 544 (1)

Epidemiology of Foodborne and Diarrheal Diseases (Fall)

Fields, Brown, Griffin

This course covers the basic epidemiology of infectious foodborne and diarrheal diseases of the United States and the world. Uses the study of these diseases and outbreak investigations to develop broadly applicable epidemiologic skills. Explores dynamic relationship between changing global environment and human health distribution, changes in the human population. Prerequisite/concurrent: EPI 504, or EPI 530.
EPI 546 (2)

Methods in HIV Epidemiology (Spring)

Guest, Sanchez

Prerequisites: EPI 530 and BIOS 500 or instructor permission. Explores the epidemiology of the HIV epidemic in the US through a detailed examination of the major types of epidemiologic studies that have led to our current understanding of the epidemic. Students gain an understanding of important issues in the epidemiology of HIV in the US, and, as importantly, increase their understanding of the strengths and weaknesses of various epidemiologic study designs and the interpretation of data from such studies.
EPI 547 (2)

Public Health Applications of Molecular Epidemiology (Spring, odd years)


Molecular epidemiology encompasses topics beyond the recent era of “-omics.” Biospecimens have been analyzed to evaluate exposures and health states for decades. We will discuss a range of public health applications of molecular epidemiology. For each, we will review the biospecimen and analyte, how the biospecimen is collected and analyzed, and how the results are used, or may be used, to protect or improve public health. Examples of topics we will study include (a) cholesterol & triglycerides associated with heart disease, (b) blood alcohol & breathalyzer associated with injury, (c) illicit drug screening and employment, and (d) serum δ13C as a marker of dietary sweets intake. Prerequisite: EPI 530 and knowledge molecular biology (DNA, RNA, proteins etc).
EPI 550 (2)

Epidemiology and Dynamics of STD and HIV Transmission (Fall)


This course explores the social, biologic, and public health issues of sexually transmitted diseases and their overall importance in public health. Topics include the basic biology and epidemiology of the major STDs, the implication of transmission models for prevention, and psychosocial, behavioral, and economic aspects of STD/HIV. Prerequisite/concurrent: EPI 504,  or EPI 530 (concurrent okay). Cross-listed with GH 550.
EPI 552 (2)

Human Genome Epidemiology (Spring)

Gwinn, Sun

This course will introduce students to applications of epidemiologic methods and approaches to evaluating the use of human genetic discoveries in the practice of medicine and public health in the 21st century. With the completion of the human genome project, the epidemiologic approach is now urgently needed to assess the prevalence of genetic variation in the population, to characterize the burden of disease associated with genetic variation and with gene- environment interaction, and to evaluate the impact of genetic tests in reducing morbidity and mortality. At the end of the course, participants should be able to identify types of information needed to translate genetic discoveries into medicine and public health and be able to review and evaluate such information in the scientific literature. The course is designed for public health students interested in the intersection of epidemiology, genetics, preventive medicine, and health policy. Prerequisite/Concurrent: EPI 504 or EPI 530.
EPI 553 (2)

Writing and Presenting Epidemiologic Research (Fall)


The primary objective of this course is to develop skills in planning, writing, and presenting
epidemiologic information in scientific reports, journal manuscripts, scientific conference posters and
oral presentations, and MPH theses or PhD dissertations. Prerequisite: EPI 530, EPI 534 and BIOS 500 or instructor permission.
EPI 554 (3)

Religion & Public Health
(Fall or Spring, May not be offered every year)


This course will provide graduate students and advanced undergraduate students with a sociologically-oriented interdisciplinary survey of research on the intersection of public health and religious practices and beliefs in individuals and populations. Religion is one factor among many others in social environment that to some extent determines the health in the lives of individuals, their families and social networks, health professionals, and the institutions in which they interact. The course will emphasize evidence from quantitative social sciences and epidemiology, the role of religion in the historical development of public health institutions, and the theoretical social science origins of religion and health research. Under the large umbrella of health research, we will be attempting to map the part of the field that is distinctively oriented to public health, rather than to medicine.
EPI 556 (2)

Applied Genomic Epidemiology (Fall)


Genomic epidemiology is an increasingly important approach to studying disease risks in populations. This course will introduce the basic genetic principles as they apply to the identification of genetic variations associated with disease; illustrate the population and quantitative genetic concepts that are necessary to study the relationship between genetic variation and disease variation in populations; and provide hands-on experience to address the analytical needs for conducting genomic epidemiologic research. Studentswill gain experience with R and PLINK using high dimensional genetic data. BIOS 500 and EPI 552 or instructor permission, Knowledge of R is recommended.
EPI 558 (2)

Global Issues in Antimicrobial Resistance (Spring)


Develops tools to understand the microbiological, behavioral, and economic factors that contribute to the expanding epidemic of infectious diseases that may become untreatable due to the emergence of resistance. Provides a framework for intervention studies. Cross-listed with GH 558.
EPI 560 (2)

Cardiovascular Disease Epidemiology (Spring)


Emphasis is placed upon the distribution and determinants of cardiovascular disease within the population. Research design and analysis are not the primary focus of the course, but methodological issues are considered when pertinent to findings interpretation. Prerequisites: EPI 530 or EPI 504.
EPI 562 (2)

Emerging Infectious Diseases


This course examines factors that contribute to the emergence and re-emergence of infectious diseases, and provides a framework for assessing the public health threat from infectious diseases and for recommending an appropriate response. Fundamental principles of infectious disease surveillance and epidemiology as well as pathogenesis will be addressed. Previous course work in microbiology strongly preferred. Prerequisite/concurrent: EPI 504, or EPI 530 or permission of instructor. Cross-listed with GH 518.
EPI 564 (2)

Public Health Preparedness (Fall)


Acquaints students with major topics associated with past and potential future acts of bioterrorism. Includes familiarity with disease agents and their pathology, epidemiology, and means of dispersion. Students will become knowledgeable in the key elements of planning the response to bioterrorism at all functioning levels of public health. Cross-listed with GH 564.
EPI 565 (2)

Data Sources and Methods in MCH Epidemiology (Spring)


This course introduces students to data sources and methods commonly used by epidemiologists in state or provincial health departments. Data sources include websites, census, vital statistics, surveys (PRAMS). Methods include record linkage, questionnaire design, mapping, trend analysis, perinatal periods of risk, cluster investigation, small number analysis and secondary data analysis. Prerequisites: EPI 530 or EPI 504, BIOS 500 and knowledge of SAS.

EPI 566 (2)

Immunization Programs and Policies (Spring)


Provides an introduction to the entire spectrum of vaccines and immunization: from basic bench research through testing, licensure, and use; program design, implementation and evaluation; and social, economic, and political factors affecting the use of vaccines. Primary emphasis will be on the international setting but examples will also be taken from developed countries. Cross-listed with GH 566.

EPI 567 (2)

Epidemiology of Aging Populations (Spring)

Platinga, Idler, Johnson

This course introduces the student to the epidemiology of aging populations. Aging and health are characteristics of both individuals and populations. Students will be introduced to the distribution of and trends in chronic disease morbidity, functional disability, and mortality, with a focus on methods for epidemiologic research in aging populations. This introductory survey will be grounded in a site visit and descriptive paper dealing with aging populations. Prerequisites: EPI 537 or instructor permission.

EPI 568 (2)

Bias Analysis (Fall)


Observational epidemiologic studies yield estimates of effect that differ from the true effect because of random error and systematic error. Epidemiologists design studies and analyses to minimize both sources of error. When presenting results, epidemiologists use statistics to quantify the impact of random error on estimates of effect, but often only qualitatively describe residual systematic error (uncontrolled bias). Bias analysis provides one method of quantifying residual systematic
error. Students in this course will learn how to use simple, multidimensional, and probabilistic bias analyses to account for systematic error in their estimates of effect. Students should expect to gain new skills, as the emphasis of the course will be on the implementation and conduct of bias analysis, rather than statistical theory. Pre-requisites: EPI 530, EPI 534 and EPI 591U or instructor permission.

EPI 570 (3)

Infectious Disease Dynamics: Theories and Models (Spring)



Infectious disease dynamics involve complex processes in which there are often dependencies betweeen individual-level and popultion-level disease risks. this course presents the thoery, mathematical framework, and quantitative methods for investigating the mechanics of infectious disease dynamics to understand these processes. he focus will be on learning mechanistic (also called mathematical) models for epidemics. Students will: learn why thesemodels are used in infectious disease research compared to other quantitative methods; practice how to rad and evaluate the epidemiological literature on epidemic modeling across many infectious disease types; and gain hands-on skills to develop computational models for epidemic spread. Pre-requisites: EPI 540/GH 517 and EPI 740 or instructor premission. Knowledge of R is required.

EPI 584 (2)

Epidemiology of Cancer (Fall)


The primary objective of this course is for the student to gain basic knowledge about cancer issues and methodologies relevant to investigating cancer etiology, prevention, and control using epidemiologic methods. Secondary objectives are for the student to gain experiences in critiquing published cancer epidemiology articles and conducting a literature review and writing a summary of a topic in cancer epidemiology. Pre-requisites: EPI 504 or 530 or instructor permission.

EPI 585 (2)

Advanced Topics in Cancer EPI (Spring, may not be offered every year)


The primary objective of this course is for the student to gain comprehensive knowledge about cancer and methodologies and current issues central to cancer epidemiology. It is assumed that students enrolled in the course have successfully completed introductory courses in epidemiology as well as an introductory course in cancer epidemiology (EPI 7584 “The Epidemiology of Cancer” or have comparable background in cancer and/or in the epidemiology of chronic diseases). The course builds on knowledge gained in other courses (including EPI 584) and covers the biological basis of carcinogenesis and its implications for epidemiologic research, an integrated view of current issues central to cancer epidemiology, an in-depth examination of methodological issues relevant to cancer research, and integration of knowledge across cancer sites. Secondary objectives are for the student to gain experiences in critiquing published cancer epidemiology articles and writing a short proposal on a topic related to current issues in cancer epidemiology. Prerequisites: EPI 585 or instructor permission.

EPI 589 (2)

Psychosocial Epidemiology (Fall)


Epidemiology is the study of the distribution and determinants of disease. Psychosocial Epidemiology is a growing subfield of Epidemiology that examines how psychological and social factors influence physical health and disease in human populations. Because the field of Psychosocial Epidemiology is heavily influenced by observational data, the concepts of confounding, mediation and effect modification will be emphasized throughout the course. Class sessions will consist of presentations by the professor; interactive discussions about key topics, assigned readings and in-class assignments; viewing and discussion of educational DVDs; and student presentations. Pre-requisites: EPI 504 or EPI 530.

EPI 590R (VC)

Epidemiology Seminar (Spring)

Various topics by Epi faculty. Current topics include Systematic Reviews and Meta-Analysis, Prediction Research, Epidemiology of Respiratory Illness, Obesity Epidemiology, and Infectious Disease Dynamics.

EPI 591L (2)

Methods in Nutritional Epidemiology (Fall)


Pre-requisites: EPI 530, EPI 533 or instructor permission. Experience with SAS preferred. This course is designed for students interested in studies of diet and health outcomes. The course provides an overview of methods for estimating dietary intakes. Issues related to the collection, processing, analysis and manipulation of dietary data in relation to foods dietary patterns, nutrients, and dietary supplements will also be addressed. Students will also have theopportunity to apply methods for manipulating dietary data including understanding variation in diet, comparing methods for energy adjustment, manipulating raw data to create food grouping variables for dietary pattern analysis and calculating a dietary score.

EPI 591S (2)

Social Epidemiology (Fall, Spring)


This course will focus on the contribution of social factors to health and disease in human populations. With an emphasis on both theory and methods, seven topics of contemporary interest to public health research will be covered in depth: (1) social status; (2) race, ethnicity and racism; (3) geography/place; (4) immigration; (5) health literacy; (6) stress; and (7) social support. Pre-requisites: EPI 504 or EPI 530.

EPI 591U (3)

Application of Epidemiologic Concepts with Lab (Spring)


Prerequisites: EPI 530, BIOS 500, EPI 533 or instructor permission. Provides a conceptual overview of causality, bias (including confounding, information bias, and selection bias), and effect measure modification. A semester-long lab project illustrates how these topics are addressed analytically and through study design. This course is required for Epidemiology and Global Epidemiology students.

EPI 594 (3)

Methods in Advanced Social EPI (Spring)


This advanced graduate course is a blended seminar and lab format introducing students to some of the challenges of quantitative research in modern social epidemiology. With a focus on application, the course explores the intersection of social epidemiologic theory and quantitative methods for better understanding multilevel causal mechanisms, complex social selection and confounding, and the spatial patterning of exposures, covariates and health outcomes.
Pre-requisites: INFO 530 or INFO 532, EPI 740 and EPI 591S or BSHE 535 or instructor permission.

EPI 595R (0)

Practicum (Fall, Spring, Summer)

Enables students to apply skills and knowledge through a supervised field training experience in a public health setting that complements the student interest and career goals.

EPI 597R (VC)

Directed Study

EPI 599R (4)

Thesis (Fall, Spring, Summer)

Enables students to apply the principles and methods learned in an academic setting through the preparation of a monograph that embodies original research applicable to public health, incorporating a hypothesis that has been successfully evaluated with appropriate statistical and epidemiological techniques and is potentially publishable and has public health impact. Graded S/U.

EPI 730

Grant Writing (Spring)


PhD students only. This course provides an opportunity to apply information learned in methods and substantive courses to the very practical task of gaining funding for research projects.
EPI 731

Analytical Foundation of Epidemiology (Spring)


PhD students only. Designed specifically for Epidemiology PhD students to learn statistical theory in the context of epidemiologic concepts and examples. The aim of the course is for students to understand the theories that underlie the statistical techniques used in epidemiologic research and to enhance critical think and integration of this material with broader epiemiologic principles.
EPI 738 (2)

Advanced Epidemiologic Methods I (Spring)


Covers a wide variety of topics in epidemiologic methodology. Topics will include basic epidemiologic measures, confounding, misclassification, selection bias, types of case-control studies, Berkson of epidemiologic parameters. Prerequisite: EPI 530, EPI 534, BIOS 500, BIOS 501 (EPI 534 and BIOS 501 may be taken concurrently). Doctoral student section.
EPI 739 (2)

Advanced Epidemiological Methods II (Fall)


Deals with a wide variety of topics in quantitative epidemiological methodology. Topics will include concepts of study design and the relationship to hazard rates and ratios, conditional logistic regression, polytomous logistic regression, continuation odds ratio models, and Poisson regression. Prerequisite: EPI 530, EPI 534, BIOS 500, BIOS 510 (may be taken concurrently). Permission required.
EPI 740 (3)

Epidemiological Modeling (Fall)


Students in this course become familiar with methods for analyzing multivariable data sets in order to evaluate epidemiological research questions involving relationships between exposure and disease variables. Prerequisites: EPI 530, EPI 534, BIOS 500, and BIOS 591P or BIOS 501. Previous coursework/experience in epidemiologic methods and regression required.
EPI 744 (2)

Pediatric and Perinatal Epidemiology (Fall)


A survey course to review the current knowledge about various topics related to factors that affect pregnancy outcome. Introduces methodologic issues that are specific to these studies. Methodologic issues are addressed in the context of choosing study design options and evaluating current research including choice of study populations, prevalence issues, selection issues, confounding, misclassification, and etiologic heterogeneity. Prerequisites: EPI 530 and EPI 534 or permission of instructor.

EPI 746 (2)

Reproductive Epidemiology (Spring)


This course reviews the epidemiology of human reproductive function and the methodologic issues involved in studying reproduction. Topics include male and female infertility, pregnancy loss, the impact of infectious diseases on reproduction, contraceptive efficacy, unintended pregnancy, and environmental and occupational impacts on reproduction. Prerequisite: EPI 504 or EPI 530.

EPI 747 (2)

Methods in Occupational and Environmental Epidemiology (Fall)


Explores design and analysis issues specific to occupational and environmental epidemiology. Case studies representative of a variety of exposures, outcomes, and study designs are used to illustrate the application of epidemiological principles to the study of exposures occurring in the workplace and in the general environment. Prerequisites: EPI 530, EPI 534, BIOS 500, BIOS 501/BIOS 591P, or permission of instructor. Cross-listed with EHS 747.

EPI 750 (3)

Analysis of Longitudinal Data in Epidemiological Research (Spring)

Students will become familiar with methods for analyzing longitudinal data sets to evaluate epidemiological research involving relationships between exposure and disease variables.
Prerequisite: EPI 740. Permission required.
EPI 790R (1)

Epidemiology PhD Journal Club (Fall, Spring)


Presents discussions by invited guests, faculty, and students of special topics and research findings.
PhD students only.
EPI 791 (1) Teaching Epidemiology This course provides an opportunity for students to learn and apply principles and skills involved in organizing and teaching an introductory level course in epidemiologic methods. The course is designed to be taken concordantly with the student’s teaching assistantship experience. Topics include using Blackboard, leading and facilitating discussion of epidemiologic topics and assignments, developing and evaluating laboratory exercises and exams, and diversity in the classroom (both culturally and with respect to learning styles) Discussions of specific labs will cover objectives and key concepts for each. There will also be an opportunity for students to discuss teaching issues and challenges with their peers and the instructor, and to offer adviceandsolutions basedon their experience.
EPI PhD students only.
EPI 798/799R (VC) Research
(Fall, Spring, Summer)

Dissertation research. PhD students only.

TATTO 600 TATTO summer course (PhDs only)

TATTO 605 Teaching assistant assignment (PhDs only)

TATTO 610 Teaching associate assignment (PhDs only)

RES 999/PUBH MPH/MSPH graduate in residence Full-time status; must have completed all course hours.

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