MSPH, 2001, University of North Carolina
PhD , 2005, University of North Carolina
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Career Overview:
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Dr. Mia M. Gaudet joined the research staff at American Cancer Society in 2010 following previous faculty position at Memorial Sloan-Kettering Cancer Center and Albert Einstein College of Medicine. Dr. Gaudet is currently the Director of Genetic Epidemiology of the Epidemiology Research Program.
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Areas of Interest/Research:
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Cancer Prevention
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Selected Research Projects:
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Dr. Gaudet is a cancer epidemiologist with primary interests in genetic susceptibility, hormonal pathways, and the etiology and prognosis of breast and endometrial cancers. She has evaluated the role of genetic variation in relationship to cancer risk using candidate and genome-wide approaches in high risk and general populations. She is also conducting research in biological mechanisms mediating the association between breast and endometrial cancer and energy imbalance, including sex steroid hormones, insulin/insulin growth factor-axis, adipokines, and metabolomic profiles. By examining both serum markers and genetic variants in these pathways, she is utilizing a comprehensive approach to determine how energy imbalance relates to cancers of the breast and endometrium in several large prospective and case-control studies. Aberrations in these pathways may alter expression of important oncogenes and tumor suppressor genes leading to cancer initiation and progression.
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Selected Publications:
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Gaudet MM, Patel AV, Sun J, Hildebrand JS, McCullough ML, Chen AY, Gapstur SM.
Prospective studies of body mass index with head and neck cancer incidence and mortality.
Cancer Epidemiol Biomarkers Prev , 21: 497-503, 2012.
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Gaudet MM, Falk RT, Stevens RD, Gunter MJ, Bain JR, Pfeiffer RM, Potischman N, Lissowska J, Peplonska B, Brinton LA, Garcia-Closas M, Newgard CB, Sherman ME.
Analysis of serum metabolic profiles in women with endometrial cancer and controls in a population-based case-control study.
J Clin Endocrinol Metab , 2012.
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Gaudet MM, Patel AV, Sun J, Teras LR, Gapstur SM.
Tubal Sterilization and Breast Cancer Incidence: Results from the Cancer Prevention Study-II Nutrition Cohort and Meta-Analysis.
Am J Epidemiol , 2012.
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Gaudet MM, Press MF, Haile RW, Lynch CF, Glaser SL, Schildkraut J, Gammon MD, Douglas Thompson W, Bernstein JL.
Risk factors by molecular subtypes of breast cancer across a population-based study of women 56 years or younger.
Breast Cancer Res Treat , 130: 587-97, 2011.
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Gaudet MM, Kirchhoff T, Green T, Vijai J, Korn JM, Guiducci C, Segrè AV, McGee K, McGuffog L, Kartsonaki C, Morrison J, Healey S, Sinilnikova OM, Stoppa-Lyonnet D, et al.
Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer.
PLoS Genet , 28: 2010.
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Link to this page: http://www.sph.emory.edu/faculty/RSPH_MGaudet
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