Ph.D. in Biostatistics, 2010, Johns Hopkins University
MHS in Bioinformatics, 2010, Johns Hopkins University
M.S. in Electrical Engineering, 2000, Iowa State University
B.S. in Electrical Engineering, 1996, Tsinghua University
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Career Overview:
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I joined the Department of Biostatatstics and Bioinformatics in 2010 as an assistant professor, after obtaining my Ph.D. degree from Johns Hopkins University. My researches have been mainly focused on bioinformatics and computational biology. I'm particularly interested in developing statistical methods and computational tools for interpreting large scale genomic data from high-throughput technologies such as microarrays and second generation sequencing.
I'm also interested in general machine learning, pattern recognition and large scale data mining methods with applications to biological and medical data.
I collaborate closely with researchers working on epigenetics to characterize DNA and different types of histone methylations.
For more details please visit my personal webpage at http://www.sph.emory.edu/~hwu/.
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Areas of Interest/Research:
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Bioinformatics
Statistical Modeling
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Selected Publications:
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, Ji H
JAMIE: joint analysis of multiple ChIP-chip experiments
Bioinformatics , 26: 1864-1870, 2010.
http://bioinformatics.oxfordjournals.org/cgi/content/abstrac...
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, Irizarry RA, Corrada Bravo H.
Intensity normalization improves color calling in SOLiD sequencing
Nature Method , 7: 336-337, 2010.
http://www.nature.com/nmeth/journal/v7/n5/full/nmeth0510-336...
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, Caffo B, Jaffee HA, Irizarry RA
Redefining CpG islands using hidden Markov models
Biostatistics , 11(3): 499-514, 2010.
http://biostatistics.oxfordjournals.org/cgi/content/abstract...
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Wen B, , Shinkai Y, Irizarry RA, Feinberg AP
Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells
Nature Genetics , 41: 246-250, 2009.
http://www.nature.com/ng/journal/v41/n2/abs/ng.297.html
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Wen B*, *, Bjornsson H, Green RD, Irizarry RA, Feinberg AP (* joint first authors)
Overlapping euchromatin/heterochromatin- associated marks are enriched in imprinted gene regions and predict allele-specific modification
Genome Research , 18: 1806-1813, 2008.
http://genome.cshlp.org/content/18/11/1806.full.pdf+html
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Link to this page: http://www.sph.emory.edu/faculty/HWU30
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